陈士林
陈士林，中国中医科学院首席研究员，国际欧亚科学院院士，CGCM（中药全球化联盟）副主席、中国质量协会中药分会会长；兼任香港浸会大学荣誉教授、日本东京药科大学客座教授、教育部“长江学者和创新团队计划”创新团队负责人等。曾任六碗鱼子酱刻晴满香阁所长、中国医学科学院药用植物研究所所长、世界卫生组织传统医学合作中心主任， 香港理工大学客座教授，并在英国皇家植物园丘园接受专业培训、哈佛医学院Mclean医院做访问学者等。现担任APSB，Chinese Medicine，CHM，《药学学报》等刊副主编。获得第二届全国创新争先奖章。
陈士林在国际上创建了基于ITS2的中草药DNA条形码鉴定方法体系，完成专著《中国药典中药材DNA条形码标准序列》，从基因层面解决中草药物种真伪鉴定的难题，被评为2016中国十大医学进展；
通过全基因组解析提出灵芝为首个中药基原药用模式真菌，被Nature China 选为中国最佳研究亮点推介；完成并发表人参、丹参、赤芝、菊花、卷柏、穿心莲、紫芝、紫苏、黄连 等全基因组图谱和相关组学研究，成功培育并获批８个中药材新品种证书或良种证书，主编并开拓创立《本草基因组学》学科并由科学出版社出版，列为全国高等医药院校规划教材，奠定药用植物分子遗传学基础；完成并编著《中国中药材产地生态适宜性数值区划》，避免中药材盲目引种栽培，主持无公害种植项目成功推广应用；
获吴阶平医药创新奖、Agilent Thought Leadership Award等荣誉；获国家科技进步二等奖3项。获国家发明专利和美国专利授权36项 ，发表论文500余篇，其中SCI论文300余篇，包括国际著名期刊Nature Communications，Mol Plant，PNAS等。连续六年入选Elsevier高被引中国学者榜单 。
近期主要论文：
1. Yujun Zhang,Qi Shen, Liang Leng, Dong Zhang, Sha Chen, Yuhua Shi, Zemin Ning & Shilin Chen Incipient diploidization of the medicinal plant Perilla within 10,000 years，Nature Communications volume 12, Article number: 5508 (2021)
2. Shilin Chen*.; Xu, J.; Liu, C.; Zhu, Y.; Nelson, D. R.; Zhou, S.; Li, C.; Wang, L.; Guo, X.; Sun, Y.; H Luo, Y Li, J Song, B Henrissat, A Levasseur, J Qian, J Li, X Luo, L Shi, LHe, L Xiang, X Xu, Y Niu, Q Li, Mira V. Han, H Yan, J Zhang, H Chen, A Lv, ZWang, M Liu, David C. Schwartz & C Sun*. Genome sequence of the model medicinal mushroom Ganoderma lucidum. Nature Communications 2012, 3, 913.
3. Liu, Y., Wang, B., Shu, Set al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nature Communications 12,3276(2021). http://doi.org/10.1038/s41467-021-23611-0.
4. Chen S.*, Song, J., Sun, C., Xu, J., Zhu, Y., Verpoorte, R., Fan, T.-P*. Herbal genomics: Examining the biology of traditional medicines. Science 2015,347(6219),S27-S29 .
5. China Plant BOL Group, DZ Li et al., Comparative analysis of a large dataset indicates that internal transcribed spacer (ITS) should be incorportated into the core barcode for seed plants. PNAS, 2011,108:19641-19646.
6. Song, C; Liu, Y; Song, A; Dong, G; Zhao, H; Sun, W; Ramakrishnan, Shyam; Wang, Y; Wang, S; Li, T; Niu, Y; Jiang, J; Dong, B; Xia, Y; Chen, S; Hu, Z; Chen, F; Chen, Shilin, The Chrysanthemum nankingense genome provides insights into the evolution and diversification of chrysanthemum flowers and medicinal traits. Molecular plant, 2018 Vol: 11（12）: 1482-1491
7. Mengyue Guo、Xiaohui Pang、Yanqin Xu、Wenjun Jiang、Baosheng Liao、Jingsheng Yu、Jiang Xu、Jingyuan Song、Shilin Chen Plastid genome data provide new insights into the phylogeny and evolution of the genus Epimedium Journal of Advanced Research 2021
8. Xu J , Chu Y, Liao B, Xiao S, Yin Q, Bai R, Su H, Dong L, Li X, Qian J, Zhang J, Zhang Y, Zhang X, Wu M, Zhang J, Li G, Zhang L, Chang Z, Zhang Y, Jia Z, Liu Z, Daniel Afreh, Ruth Nahurira8, Zhang L, Cheng R, Zhu Y, Zhu G, Rao W, Zhou C, Qiao L, Huang Z, Cheng Yung-Chi, Chen Shilin, Panax ginseng genome examination for ginsenoside biosynthesis GigaScience 2017, 6(11):1-15.
9. Sun W; Leng L; Yin Q; Xu M; Huang M; Xu Z; Zhang Y; Yao H; Wang C; Xiong C; Jiang C; Xie N; Zheng X; Wang Y; Song C; Reuben J. Peters，Chen S;The medicinal plant Andrographispaniculate genome provides insight into biosynthesis of the bioactive diterpenoid neoandrographolide,Plant J 2018
10. Luo L, Jiang J, Wang C, Fitzgerald M, Hu W, Zhou Y, Zhang H, Chen S*. Analysis on herbal medicines utilized for treatment of COVID-19. APSB 2020(7), 10: 1192-1204.
11. Luo L, Dong L, Huang Q, Ma S, Fantke P, Li J, Jiang J, Fitzgerald M, Yang J, Jia Z, Zhang J, Wang H, Dai Y, Zhu G, Xing Z, Liang Y, Li M, Wei G, Song J, Wei J, Peng C, Zhang H, Zhang W, Wang S, Mizuno K, Marco A, Wu L, Xu J, Xiong C, Chen S*. Detection and risk assessments of multi-pesticides in 1771 cultivated herbal medicines by GC/MS-MS and LC/MS-MS. Chemosphere. 2021,262:127477.
12. Z Xu, T Xin, Dorothea Bartels,Y Li, W Gu,H Yao,S Liu,H Yu,X Pu, J Zhou, J Xu, C Xi ,H Lei Jingyuan Song,Shilin Chen.Genome analysis of the ancient tracheophyte Selaginella tamariscinareveals evolutionary features relevant to the acquisition of desiccation tolerance. Mol Plant 2018.
13. Xu, Z.; Peters, R. J.; Weirather, J.; Luo, H.; Liao, B.; Zhang, X.; Zhu, Y.; Ji, A.; Zhang, B.; Hu, S.; Au, K. F.; Song, J*.; Shilin Chen*., Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis. The Plant Journal 2015.
14. Shilin Chen*.; Pang, X.; Song, J.; Shi, L.; Yao, H.; Han, J.; Leon, C., A renaissance in herbal medicine identification: from morphology to DNA.Biotechnology advances 2014, 32 (7), 1237-1244.
15. H Xu, J Song, H Luo, Y Zhang, Q Li, Y Zhu, J Xu, Y Li, C Song, B Wang, W Sun, G Shen, X Zhang, J Qian, A Ji, Z Xu, X Luo, L He, C Li, C Sun, H Yan, G Cui, X Li, Xi Li, J Wei, J Liu,Y Wang, A Hayward, D Nelson, Z Ning, RJ. Peters, X Qi, S Chen. Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza Mol Plant 2016, Volume 9, Issue 6, p949–952.
16. Zheng X, An W, Yao H, Xu J, Chen S*.Rapid authentification of the poisonous plant Gelsemium elegans by combining Filter-Paper-Based DNA extraction and RPA-LFD detection. Engineering 2021,7(1):14.16.
17. Li, X.; Yang, Y.; Henry, R. J.; Rossetto, M.; Wang, Y.; ShiLin Chen*, Plant DNA barcoding: from gene to genome. Biological Reviews 2015, 90 (1), 157-166.
18. Li, Q.; Li, Y.; Song, J.*; Xu, H.; Xu, J.; Zhu, Y.; Li, X.; Gao, H.; Dong, L.; Qian, J.; Sun, C, Shilin Chen*., High-accuracy de novo assembly and SNP detection of chloroplast genomes using a SMRT circular consensus sequencing strategy. New Phytologist 2014, 204 (4), 1041-1049.
19. LL Dong, J Xu ,Y Li,H Fang,W Niu,X Li,Y Zhang,W Ding,SL Chen, Manipulation of microbial community in the rhizosphere alleviates the replanting issues in Panax ginseng。Soil Biology and Biochemistry Volume 125, October 2018, Pages 64-74
20. R Shi, Z Hu, H Lu, L Liu, L Xu, Y Liu, H Wu, B Huang, G Zhang,* S Chen,* F Yang*, Hierarchical Nanostructuring Array Enhances Mid-Hybridization for Accurate Herbal Identification via ITS2 DNA Barcode. Analytical Chemistry, 2019, doi: 10.1021/acs.analchem.9b04687.
终审：小管
用户登录